World Heart Day is celebrated every year on 29 September

In May 2012, world leaders committed to reducing global mortality from non-communicable diseases (NCDs) by 25% by 2025. Cardiovascular disease (CVD) is accountable for nearly half of all NCD deaths making it the world’s number one killer. World Heart Day is, therefore, the perfect platform for the CVD community to unite in the fight against CVD and reduce the global disease burden.

Created by the World Heart Federation, World Heart Day informs people around the globe that CVD, including heart disease and stroke, is the world’s leading cause of death claiming 17.9 million lives each year, and highlights the actions that individuals can take to prevent and control CVD. It aims to drive action to educate people that by controlling risk factors such as tobacco use, unhealthy diet and physical inactivity, at least 80% of premature deaths from heart disease and stroke could be avoided.

World Heart Day is a global campaign during which individuals, families, communities, and governments around the world participate in activities to take charge of their heart health and that of others. Through this campaign, the World Heart Federation unites people from all countries and backgrounds in the fight against the CVD burden and inspires and drives international action to encourage heart-healthy living across the world. We and our members believe in a world where heart health for everyone is a fundamental human right and a crucial element of global health justice.

After two weeks on mechanical ventilation and after 4 cycles of hemofiltration, our 61-year-old patient from Berovo goes home with a negative SARS-CoV-2 test

After a month stay in our Clinic, or more specifically, in the Department where patients tested positive for the SARS-CoV-2 virus are treated, a patient who has gone through a difficult yet successful treatment process goes home.

The patient was treated in our Clinic for a month and was admitted in extremely severe general condition, positive for Coronavirus, with his body temperature above 38 degrees Celsius.

Immediately after admission, the patient was placed on non-invasive monitoring where we could monitor the patient’s vital parameters and the required laboratory, microbiological and genetic analyses were performed.

The analyses results showed elevated levels of inflammatory markers, leukocytes, CRP, procalcitonin as well as elevated D-dimer, LDH and interleukin 6 levels.

Applying our medical knowledge and following the latest recommendations for treatment of patients positive for Covid-19, we base part of the treatment of critically ill patients on blood purification that is based on the method of chemosorption of cytokines and other inflammatory mediators.

The patient was placed on veno-venous hemofiltration using an Oxiris filter and due to inversion of the gas analyses, low peripheral saturation as well as the X-ray findings of acute respiratory distress syndrome, the patient was intubated and placed on mechanical ventilation.

The patient underwent 4 cycles of hemofiltration. After the fourth cycle of hemofiltration, an improvement in his overall general condition and all the findings could be noticed.

After spending almost two weeks on a mechanical ventilator, the patient was extubated, or removed from the machine. The patient leaves our Clinic with a negative Coronavirus test and in a good and stable condition.

 

 

Zan Mitrev Clinical Hospital with the most modern Centre for Women’s Health in the region

Zan Mitrev Clinical Hospital has opened its Complete Breast Treatment Centre, which is the most modern centre for women’s health in the region, offering a wide range of medical services and state-of-the-art technology to assist in breast cancer diagnosis and surgery.

With the purchase of the latest Mammomat, the Zan Mitrev Clinical Hospital completes the equipping of its Centre for Women’s Health. The Selenia Dimensions 6000 Mammomat with ergonomic design provides comfortable and painless imaging and gives a clear view of the breast, which reduces the number of unnecessary biopsies.

With its superior 3-D technology, the Mammomat provides a scan time of 3.7 seconds and a minimal radiation dose to patients. At the same time, a large number of projections are provided from all angles, which gives a comprehensive and accurate view of the breast. 3D mammography increases the capability of early detection of cancers by 20-65%.

3D mammography – tomosynthesis reduces the number of false-positive findings, it is especially useful in women with dense breast tissue, allows early detection of cancer with a clear view of the lesion and reduces the number of unnecessary biopsies through the guided biopsy system.

The new Centre for Women’s Health in the Zan Mitrev Clinical Hospital is equipped with the latest technology for diagnostics, mammography and breast surgery and operates in synergy with all other departments that perform surgical interventions on various types of cancer.

In anticipation of October, the breast cancer awareness month, we offer a 30% discount from the regular price of 3D mammography.

For the first time in our country, an ECMO intervention was performed on a patient infected with COVID-19

To save another life, for the first time in our country, ECMO (Extracorporeal Membrane Oxygenation) was performed on a critically ill patient with COVID-19 infection, using a CytoSorb filter.

Extracorporeal membrane oxygenation (ECMO) is a modified type of cardiopulmonary bridging used as temporary support for patients with impaired respiratory or cardiac function. The main components of an ECMO machine are a membrane oxygenator, through which blood is diffused through a semipermeable membrane to remove carbon dioxide.

The patient was admitted to the Zan Mitrev Clinical Hospital in an extremely severe general condition with acute respiratory distress syndrome, with low peripheral saturation, shortness of breath and fever up to 39C. The patient was immediately intubated and placed on mechanical ventilation. Due to the inversion of the gas analyses with high pCO2 value, despite the high respiratory support and the maximum oxygen concentration, the patient was placed on extracorporeal membrane oxygenation – ECMO additionally using a CytoSorb filter.

Continually expanding our medical knowledge and following the latest recommendations for the treatment of COVID-19 patients we have started another type of blood purification based on the method of chemoabsorption of cytokines and other inflammatory mediators using a CytoSorb filter (FDA approved for the treatment of critically ill patients with COVID-19 infection) in a combination with extracorporeal membrane oxygenation (ECMO).

Zan Mitrev Clinic in constant struggle with the Coronavirus

The latest trends in the treatment of COVID-19 patients applied

During the most severe pandemic that happened to humanity after the Second World War – the COVID-19 pandemic – the main goal of our clinic is to contribute to health preservation by providing the best medical care for each patient through integrated medical practice, education and research.

COVID 19 patients are a serious challenge for treatment because there is currently no targeted therapy and treatment is mainly supportive. Patients with severe form of respiratory failure develop a severe inflammatory syndrome, which is accompanied by the release of so-called inflammatory mediators leading to multiple organ failure and death.

Following the world trends in treating the most severely ill patients in the intensive care units, we at the Zan Mitrev Clinic have been successfully using the method of blood hemofiltration with a special highly absorbent filter (Oxiris) for many years. Our success stories related to venovenous hemodiafiltration with Oxiris filter have been presented at many world-class medical conferences as well as through publications in renowned medical journals. A proof of our compliance with the highest medical standards was the official recognition of the Oxiris filtration by the FDA in April 2020 as part of the COVID-19 treatment. By increasing our medical knowledge and following the latest recommendations for the treatment of COVID-19 patients, we have started another type of blood purification based on the method of hemadsorption of cytokines and other inflammatory mediators with CytoSorb filter (FDA approved for treating critically ill COVID-19 patients). Our initial experiences of using both forms of blood purification are excellent and represent motivation and hope for curing the most severely ill patients struggling not only with COVID-19 infection but also with other forms of inflammatory diseases of both bacterial and viral nature. Filtration is slow, safe, and usually lasts between 12 and 48 hours. During that time, patients are monitored with the most sophisticated electronic laboratory system for the level of inflammatory markers (IL 6, CRP, PCT, etc.) and depending on the results, the therapy is continued or discontinued. The only limiting factor in our country is that these forms of treatment are not recognized by the Health Insurance Fund of the Republic of North Macedonia and their use, as well as continuation of the therapy when there is improvement is limited or disabled for financial reasons.

Based on the great experiences, which are published and recognized worldwide, the Zan Mitrev Clinic will continue to strive for the highest standards in care and treatment of the most severely ill patients by following the motto of Immanuel Kant: ”People have a dignity, but not a price!” Human life is priceless!