• Surgery of the heart and great vessels (cardiac surgery)
• Valvular surgery
• Bypass surgery
• Surgery of the aorta
• Combined surgery
• Congenital heart defects surgery in children and adults
• Surgery of arteries and veins (Vascular surgery)
• Surgery of peripheral arteries and veins in the extremities
• Surgery of the neck arteries (Carotid arteries)
• Surgery of large blood vessels (abdominal aorta)
• Breast surgery
• Thyroid surgery
• Treatment of chronic wounds

1991 – German Society of Thoracic and Cardiovascular Surgery
1992 – American College for Angiography
1994 – European Association for Cardio-Thoracic Surgery
2001 – European Society for Artificial Organs
2004 – Euro-Asian Bridge Society of Cardiac Surgery
2004 – International Society for Minimally Invasive Cardiac Surgery
2006 – Society of Thoracic Surgeons
2011 – Cardiothoracic Surgery Network
2011 – European Society of Cardiology
2011 – Heart Valve Society
2012 – International Society for Heart and Lung Transplantation
2013 – World Society of Cardiovascular & Thoracic Surgeons

2007 – Management Board, Goce Delchev University, Shtip, Macedonia
2011 – Macedonian Association for Nephrology, Dialysis, and Artificial Organs
2017 – Society for Cardiology of Macedonia

2003 – Humanity Award, Skopje, Macedonia

2004 – Award for Best Case Study Presentation on the 10^th Jubilee Congress for Cardiothoracic

Technology, Miami, Florida, USA.

2010 – Nomination of the Techno-College of the European Society for Technological Innovations in Cardiac Surgery for Aortic Roots Treatment.

2012 – Nomination of the Techno-College of the European Society

2020 – Award “13^th of November” as a member of the team that performed the first heart transplantation in the country

Scientific publications:

1. Beyersdorf F, Mitrev Z, Eckel L, Sarai K, Satter P: Controlled limb reperfusion as a new surgical technique to reduce postischemic syndrome. J Thorac Cardiovasc Surg 1993, 106(2):378-380.

2. Beyersdorf F, Mitrev Z, Sarai K, Eckel L, Klepzig H, Maul FD, Ihnken K, Satter P: Changing patterns of patients undergoing emergency surgical revascularization for acute coronary occlusion.

Importance of myocardial protection techniques. J Thorac Cardiovasc Surg 1993, 106(1):137-148.

3. Beyersdorf F, Sarai K, Mitrev Z, Eckel L, Ihnken K, Satter P: Studies of reperfusion injury in skeletal muscle: controlled limb reperfusion to reduce post-ischaemic syndrome. Cardiovasc Surg 1993, 1(4):330-336.

4. Beyersdorf F, Sarai K, Mitrev Z, Eckel L, Maul FD, Wendt T, Satter P: [Surgical revascularization in patients with acute myocardial infarction]. Zentralbl Chir 1993, 118(4):180-189.

5. Beyersdorf F, Sarai K, Mitrev Z, Eckel L, Ihnken K, Satter P: New surgical treatment for severe limb ischemia. Journal of investigative surgery : the official journal of the Academy of Surgical Research 1994, 7(1):61-71.

6. Mitrev Z, Beyersdorf F, Hallmann R, Poloczek Y, Ihnken K, Herold H, Unkelbach U, Zimmer G, Freisleben HJ, Satter P: Reperfusion injury in skeletal muscle: controlled limb reperfusion reduces local and systemic complications after prolonged ischaemia. Cardiovasc Surg 1994, 2(6):737-748.

7. Beyersdorf F, Mitrev Z, Ihnken K, Schmiedt W, Sarai K, Eckel L, Friesewinkel O, Matheis G, Buckberg GD: Controlled limb reperfusion in patients having cardiac operations. J Thorac Cardiovasc Surg 1996, 111(4):873-881.

8. Ihnken K, Beyersdorf F, Winkelmann BR, Mitrev Z, Unkelbach U: Experimental application of controlled limb reperfusion after incomplete ischaemia. The British journal of surgery 1996, 83(6):803-809.

9. Mitrev Z, Ihnken K, Poloczek Y, Hallmann R, Herold H, Unkelbach U, Zimmer G, Freisleben HJ, Beyersdorf S, Beyersdorf F: [Controlled reperfusion of the extremities for preventing local and systemic damage after prolonged ischemia. An experimental study with the swine model]. Zentralbl Chir 1996, 121(9):774-787.

10. Mitrev Z, Anguseva T, Vasileva A, Hristov N, Risteski P: Transplantation or alternative surgical treatment of patients with ischemic dilative cardiomyopathy and aneurysmatic dilation of the left ventricular cavity. The International journal of artificial organs 2002, 25(4):321-326.

11. Heidt MC, Menon AK, Roth P, Mitrev Z, Akinturk HK, Vogt PR: Left atrial dissection after mitral operation mimicking severe mitral regurgitation. J Thorac Cardiovasc Surg 2004, 127(2):596-597.

12. Mitrev ZK, Anguseva TN: Complex reconstruction of hydatid cyst-destructed left ventricle: a case report. Heart Surg Forum 2006, 9(1):E490-492.

13. Mitrev Z, Belostotskii V, Hristov N: Suture line reinforcement using suction-assisted bioglue application during surgery for acute aortic dissection. Interactive cardiovascular and thoracic surgery 2007, 6(2):147-149

14. Mitrev Z, Hristov N: Cardiac silhouette following a mitral valve replacement, tricuspid annuloplasty and atrioplasty of both atria. Eur J Cardiothorac Surg 2008, 34(4):905.

15. Nikolic A, Schranz D, Hristov N, Mitrev Z: Amplatzer occlusion of paravalvular leak of mitral mechanical prosthesis following a reoperation for thrombosed mitral mechanical prosthesis. Interactive cardiovascular and thoracic surgery 2008, 7(5):941-942.

16. Rosenthal VD, Maki DG, Mehta A, Alvarez-Moreno C, Leblebicioglu H, Higuera F, Cuellar LE, Madani N, Mitrev Z, Duenas L et al: International Nosocomial Infection Control Consortium report, data summary for 2002-2007, issued January 2008. American journal of infection control 2008, 36(9):627-637.

17. Abdel-Rahman U, Risteski P, Klaeffling C, Mitrev Z, Ackermann H, Matheis G, Moritz A, Beyersdorf F: The influence of controlled limb reperfusion with PGE1 on reperfusion injury after prolonged ischemia. The Journal of surgical research 2009, 155(2):293-300.

18. Mitrev Z, Belostotski V, Veljanovska L, Hristov N: Images in cardio-thoracic surgery: DeBekay repair for type III thoracoabdominal aortic aneurysm. Eur J Cardiothorac Surg 2009, 35(5):905.

19. Mitrev Z, Veljanovska L, Hristov N: Images in cardiothoracic surgery. Aorto-bilateral-femoral-bilateral-popliteal bypass for Leriche syndrome with occlusion of both superficial femoral arteries. Ann Thorac Surg 2009, 88(2):683.

20. Belostotsky V, Veljanovska L, Hristov N, Mitrev Z: Dual left anterior descending artery distribution. Interactive cardiovascular and thoracic surgery 2010, 10(4):648-649.

21. Mitrev Z: Hemodynamic monitoring for less invasive cardiovascular surgery. Lijecnicki vjesnik 2010, 132 Suppl 1:9-10.

22. Rosenthal VD, Maki DG, Jamulitrat S, Medeiros EA, Todi SK, Gomez DY, Leblebicioglu H, Abu Khader I, Miranda Novales MG, Berba R et al: International Nosocomial Infection Control Consortium (INICC) report, data summary for 2003-2008, issued June 2009. American journal of infection control 2010, 38(2):95-104.e102

23. Rosenthal VD, Maki DG, Rodrigues C, Alvarez-Moreno C, Leblebicioglu H, Sobreyra-Oropeza M, Berba R, Madani N, Medeiros EA, Cuellar LE et al: Impact of International Nosocomial Infection Control Consortium (INICC) strategy on central line-associated bloodstream infection rates in the intensive care units of 15 developing countries. Infection control and hospital epidemiology 2010, 31(12):1264-1272.

24. Hristov N, Atanasov Z, Zafirovski G, Mitrev Z: Intramuscular cavernous hemangioma in the left soleus muscle: successful surgical treatment. Interactive cardiovascular and thoracic surgery 2011, 13(5):521-522.

25. Mitrev Z, Jankulovski A, Bozinovska B, Hristov N: Surgical treatment of giant extracranial internal carotid artery aneurysm. J Vasc Surg 2011, 54(2):533.

26. Rosenthal VD, Bijie H, Maki DG, Mehta Y, Apisarnthanarak A, Medeiros EA, Leblebicioglu H, Fisher D, Alvarez-Moreno C, Khader IA et al: International Nosocomial Infection Control Consortium (INICC) report, data summary of 36 countries, for 2004-2009. American journal of infection control 2012, 40(5):396-407.

27. Rosenthal VD, Rodrigues C, Alvarez-Moreno C, Madani N, Mitrev Z, Ye G, Salomao R, Ulger F, Guanche-Garcell H, Kanj SS et al: Effectiveness of a multidimensional approach for prevention of ventilator-associated pneumonia in adult intensive care units from 14 developing countries of four continents: findings of the International Nosocomial Infection Control Consortium. Critical care medicine 2012, 40(12):3121-3128.

28. Rosenthal VD, Todi SK, Alvarez-Moreno C, Pawar M, Karlekar A, Zeggwagh AA, Mitrev Z, Udwadia FE, Navoa-Ng JA, Chakravarthy M et al: Impact of a multidimensional infection control strategy on catheter-associated urinary tract infection rates in the adult intensive care units of 15 developing countries: findings of the International Nosocomial Infection Control Consortium (INICC). Infection 2012, 40(5):517-526.

29. Mitrev ZK, Anguseva TN: Life-Threatening Surgery for Mycotic Aneurysm. Aorta (Stamford, Conn) 2013, 1(3):193-197.

30. Rosenthal VD, Pawar M, Leblebicioglu H, Navoa-Ng JA, Villamil-Gomez W, Armas-Ruiz A, Cuellar LE, Medeiros EA, Mitrev Z, Gikas A et al: Impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional hand hygiene approach over 13 years in 51 cities of 19 limited-resource countries from Latin America, Asia, the Middle East, and Europe. Infection control and hospital epidemiology 2013, 34(4):415-423.

31. Rosenthal VD, Richtmann R, Singh S, Apisarnthanarak A, Kubler A, Viet-Hung N, Ramirez-Wong FM, Portillo-Gallo JH, Toscani J, Gikas A et al: Surgical site infections, International Nosocomial Infection Control Consortium (INICC) report, data summary of 30 countries, 2005-2010. Infection control and hospital epidemiology 2013, 34(6):597-604.

32. Mitrev Zan “Cardiovascular solutions” 2013

33. Rosenthal VD, Maki DG, Mehta Y, Leblebicioglu H, Memish ZA, Al-Mousa HH, Balkhy H, Hu B, Alvarez-Moreno C, Medeiros EA et al: International Nosocomial Infection Control Consortium (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module. American journal of infection control 2014, 42(9):942-956.

34. Idrizi S, Milev I, Zafirovska P, Tosheski G, Zimbakov Z, Ampova-Sokolov V, Angjuseva T, Mitrev Z: Interventional Treatment of Pulmonary Valve Stenosis: A Single Center Experience. Open access Macedonian journal of medical sciences 2015, 3(3):408-412.

35. Klincheva M, Vilarova EA, Angjusheva T, Milev I, Idoski E, Mitrev Z: Endothelial Nitric Oxide Synthase T-786C Mutation, Prothrombin Gene Mutation (G-20210-A) and Protein S Deficiency Could Lead to Myocardial Infarction in a Very Young Male Adult. Open access Macedonian journal of medical sciences 2016, 4(1):142-145.

36. Milev I, Zafirovska P, Zimbakov Z, Idrizi S, Ampova-Sokolov V, Gorgieva E, Ilievska L, Tosheski G, Hristov N, Georgievska-Ismail L et al: Transcatheter Closure of Patent Foramen Ovale: A Single Center Experience. Open access Macedonian journal of medical sciences 2016, 4(4):613-618.

37. Rosenthal VD, Al-Abdely HM, El-Kholy AA, AlKhawaja SAA, Leblebicioglu H, Mehta Y, Rai V, Hung NV, Kanj SS, Salama MF et al: International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module. American journal of infection control 2016, 44(12):1495-1504.

38. Sakr Y, Ferrer R, Reinhart K, Beale R, Rhodes A, Moreno R, Timsit JF, Brochard L, Thompson BT, Rezende E et al: Correction to: The Intensive Care Global Study on Severe Acute Respiratory Infection (IC-GLOSSARI): a multicenter, multinational, 14-day inception cohort study. Intensive care medicine 2018, 44(1):144-152.

39. Stajkovska A, Mehandziska S, Stavrevska M, Jakovleva K, Nikchevska N, Mitrev Z, Kungulovski I, Zafiroski G, Tasic V, Kungulovski G: Trio Clinical Exome Sequencing in a Patient With Multicentric Carpotarsal Osteolysis Syndrome: First Case Report in the Balkans. Frontiers in genetics 2018, 9:113.

40. Mitev K, Neziri D, Stoicovski E, Mitrev Z. Surgical plate fixation of multiple rib fractures: a case report.J Med Case Rep. 2018 May 29;12(1):150.

41. Mitrev Z, Klincheva M, Anguseva T, Zdravkovski I, Rosalia RA. Cardiac autotransplantation and ex vivo surgical repair of giant left atrium: a case presentation.BMC Cardiovasc Disord. 2018 Dec 18;18(1):239.

42. Popevski D, Popovska-Cvetkova M, Ignevska K, Rosalia RA, Mitrev Z. Continuous venovenous hemodiafiltration using cytokine-adsorbing hemofilters as adjuvant therapy for anaerobic descending necrotizing mediastinitis: a case report.J Med Case Rep. 2019 Jul 5;13(1):205.

43. Kapedanovska-Nestorovska A, Dimovski AJ, Sterjev Z, Matevska Geskovska N, Suturkova L, Ugurov P, Mitrev Z, Rosalia R. The AKR1D1*36 (rs1872930) Allelic Variant Is Independently Associated With Clopidogrel Treatment Outcome. Pharmgenomics Pers Med. 2019 Oct 21;12:287-295.

44. Stajkovska A, Mehandziska S, Rosalia R, Stavrevska M, Janevska M, Markovska M, Kungulovski I, Mitrev Z, Kungulovski G. A Pediatric Case of Glioblastoma Multiforme Associated With a Novel Germline p.His112CysfsTer9 Mutation in the MLH1 Gene Accompanied by a p.Arg283Cys Mutation in the TP53 Gene: A Case Report.Front Genet. 2019 Oct 22;10:952.

45. Risteski P, Anguseva T, Rosalia R, Grazdani S, Klincheva M, Filipce V, Sokarovski M, Popov AF, Jovev S, Mitrev Z. Outcomes with Ventricular Assist Device Therapy for Advanced Heart Failure in North Macedonia: First Annual Report.Heart Surg Forum. 2020 Jun 26;23(4):E441-E446

46. Mehandziska S, Stajkovska A, Stavrevska M, Jakovleva K, Janevska M, Rosalia R, Kungulovski I, Mitrev Z, Kungulovski G. Workflow for the Implementation of Precision Genomics in Healthcare. Front Genet. 2020 Jun 30;11:619.

47. Fara A, Mitrev Z, Rosalia RA, Assas BM. Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines. Open Biol. 2020 Sep;10(9):200160

48. Zimoski R, Ugurov P, Veljanoska-Kiridjievska L, Hristov N, Idoski E, Gjorgon M, Milevska-Kostova N, Rosalia RA, Mitrev Z. Minimally Invasive Surgical Repair of Vertebral Artery Ostium Stenosis in Patients with Ischemic Stroke: A Single-Center Case Series. World Neurosurg. 2021 Feb;146:367-375

49. Ugurov P, Popevski D, Gramosli T, Neziri D, Vuckova D, Gjorgon M, Stoicovski E, Marinkovic S, Veljanovska-Kiridjievska L, Ignevska K, Mehandziska S, Ambarkova E, Mitrev Z, Rosalia RA. Early Initiation of Extracorporeal Blood Purification Using the AN69ST (oXiris®) Hemofilter as a Treatment Modality for COVID-19 Patients: a Single-Centre Case Series.Braz J Cardiovasc Surg. 2022 Mar 10;37(1):35-47.

50. Rosalia RA, Ugurov P, Neziri D, Despotovska S, Kostoska E, Veljanovska-Kiridjievska L, Kuzmanov D, Trifunovski A, Popevski D, Villa G, Mitrev Z. Extracorporeal Blood Purification in Moderate and Severe COVID-19 Patients: A Prospective Cohort Study. Blood Purif. 2022;51(3):233-242.

51. Mitrev Z, Risteski P, Todorovska M, Pavlovikj M, Sá MPBO, Rosalia R. Aortic Valve Neocuspidization Using Xenologous Pericardium Versus Bioprosthetic Valve Replacement. Ann Thorac Surg. 2022 Apr;113(4):1192-1199.

52. Gjorgjievska M, Mehandziska S, Stajkovska A, Pecioska-Dokuzovska S, Dimovska A, Durmish I, Ismail S, Pavlovska T, Stojchevska A, Amedi H, Andonova J, Nikolovska M, Velickovikj S, Mitrev Z, Kungulovski I, Kungulovski G. Case Report: Omicron BA.2 Subvariant of SARS-CoV-2 Outcompetes BA.1 in Two Co-infection Cases.Front Genet. 2022 Apr 12;13:892682.

53. Zafirovska P, Rosalia RA, Ismail LG, Matveeva N, Mitrev Z. Preoperative Left Ventricular Global Longitudinal Strain Identifies Aortic Stenosis Patients with Improved Postoperative Recovery of Left Ventricular Geometry: A Prospective Cohort Study. Braz J Cardiovasc Surg. 2022 May 2;37(2):161-175.

54. Gjinoska K, Nikolovski A, Stoicovski E, Mitrev Z. Unexpected intraoperative finding of a hyalinizing cholecystitis in a patient with gallbladder calculi.J Surg Case Rep. 2024 Oct 18;2024(10)

55. Nikolovski A, Gjinoska K, Kocevski Z, Stoicovski E, Mitrev Z. Giant (complex) inguinal hernia in female patient left untreated for 40 years: a case report. J Surg Case Rep. 2024 Nov 26;2024(11)

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