Prof. Dr. Milka Klincheva

2017- 2019

Sub specialization in cardiology, univ. “Goce Delcev” Stip, R. Macedonia

2013

Specialization in Internal Medicine, Medical Faculty, univ.  “St.Cyril and Methodius”, Skopje, Macedonia

2010

PhD in Physiology and Pathophysiology, IIIrd Medical Faculty, Charles University, Prague, Czech Republic

2007

Specialization in internal medicine

2000

Graduated Doctor of General Medicine at the University “St. Cyril and Methodius”, Skopje, Macedonia

2021 – present 

Assоssiate professor, Faculty of Medical Sciences, univ. “Goce Delcev”, Stip, R. Macedonia

2016 – present

Doctor specialist in internal medicine, subspecialiste kardiologie at Zan Mitrev Clinic, Skopje, Macedonia

2007-2016

Doctor specialist  in internal medicine at the special hospital for cardiac surgery “Filip II” Skopje, Macedonia

2011

Assistant professor, Faculty of Medical Sciences, univ. “Goce Delcev”, Stip, R. Macedonia

2000-2002

Doctor at the special hospital for cardiac surgery “Filip II” Skopje, Macedonia

2025             

Society of Cardiovascular Magnetic Resonance (SCMR) Level 2 certificate

2025              

EACVI Cardiac magnetic resonance (CMR) Level 2 certificate

2019 – 2021

Postgraduate course in Heart Failure, London

Procedures:
•  Transthoracic echocardiography
• Stress echocardiography
• Doppler of arterial circulation
• Coronary stress test
• 24 hour ECG and ABP Holter monitoring
• Spirometry
• Pleural puncture
• Invasive monitoring
• Magnetic resonance of the heart

• Macedonian Society of Cardiology
• European Society of Cardiology
• Еuropean Society of Heart Failure
• European Association of Cardiovascular Imaging

1. Edris AF Mahtab, Samuel A Max  Jerry Braun, Madelien V Regeer, Brian Kaufman, Joel Dunning, Bhuvaneswari Bibleraaj, Martin Andreas, Rafael Rodríguez Lecoq, Milka Klinceva, Rodney Rosalia, Roberto Lorusso, Nico Bruining , Anastasia D Egorova  „Developing a Systematic Approach for the Implementation of Medical Extended Reality Learning Modules in Cardiothoracic Health Care. JACC Adv 2025 Mar 26;4(3):101633. doi: 10.1016/j.jacadv.2025.101633 (IF 1.7)
   
2. Taseva Vasileva AM, Klincheva M, Bosevska G, Mitrev Z. Postoperative Atrial Fibrillation after Cardiac Surgery: A Review of Risk Factors, Clinical Outcomes, and Management Strategies. Open Access Maced J Med Sci [Internet]. 2025 Dec. 15 [cited 2025 Dec. 21];13(4):183-90.
3. Taseva Vasileva, A. M., Klinceva, M., Bosevska, G., & Mitrev, Z. (2025). MULTIVESSEL CORONARY ARTERY DISEASE AS A PREDICTOR OF PROLONGED POSTOPERATIVE ATRIAL FIBRILLATION AFTER CARDIAC SURGERY. KNOWLEDGE – International Journal, 73(4), 631–635. Retrieved from https://ojs.ikm.mk/index.php/kij/article/view/7948
4. Mohamad Bashir, Matti Jubouri , Abdelaziz O Surkhi , Ian M Williams , Lazar B Davidovic , Igor Koncar , Tomas Baltrūnas, Aysegul Kunt, Ömer Tanyeli , Muhammed Bayram , Murat Ugur, Giovanni Rossi , Marie-Elisabeth Stelzmueller, Arjan W J Hoksbergen, Vincen Jongkind , Luca Bertoglio, Sergio Zacà, Wassim Mansour , Pasqualino Sirignano, Mario D’Oria, Valerio Stefano Tolva, Isabelle Van Herzeele, Milka Klincheva et al. Uncomplicated Type B Aortic Dissection: A European Multicentre Cross-Sectional Evaluation. Ann Vasc Surg 2024 Dec 18:S0890-5096(24)00832-X. doi: 10.1016/j.avsg.2024.09.067. (IF 1.6)
5. Jeroen Dauw , MD, MMed; Kristina Charaya , MD, PhD; Małgorzata Lelonek, MD, PhD; Isabel Zegri-Reiriz , MD, PhD; Samer Nasr , MD; Cynthia P. Paredes-Paucar, MD; Attila Borbély, MD, PhD; Fatih Erdal, MD; Riad Benkouar, MD, PhD; Marta Cobo-Marcos , MD; Gonzalo Barge-Caballero, MD, PhD; Varghese George , MD, DMM; Cornelia Zara, MD; Noel T. Ross, MD; Diane Barker, MD; Annop Lekhakul, MD; Simone Frea, MD; Azmee M. Ghazi , MD; Dorit Knappe, MD; Nawal Doghmi , MD; Milka Klincheva, MD, PhD; Inês Fialho, MD; Virginia Bovolo, MD; Hajo Findeisen , MD; Imad A. Alhaddad , MD; Alessandro Galluzzo , MD; Rafael de la Espriella, MD; Ramzi Tabbalat, MD; Òscar Miró, MD, PhD; Jagdeep S. Singh , MBBS, MD; Petra Nijst , MD, PhD; Matthias Dupont , MD; Pieter Martens , MD, PhD; Wilfried Mullens , MD, PhD. Protocolized Natriuresis-Guided Decongestion Improves Diuretic Response: The Multicenter ENACT-HF Study.

Circ Heart Fail. 2024;17:e011105. DOI: 10.1161/CIRCHEARTFAILURE.123. (IF 8.4)

6. Jeroen Dauw, Malgorzata Lelonek, Isabel Zegri-Reiriz, Cynthia P Paredes-Paucar, Cornelia Zara, Varghese George, Marta Cobo-Marcos, Dorit Knappe, Dmitry Shchekochikhin, Annop Lekhakul, Milka Klincheva, Simone Frea, Òscar Miró, Diane Barker , Attila Borbély, Samer Nasr , Nawal Doghmi, Rafael de la Espriella , Jagdeep S Singh, Virginia Bovolo, Inês Fialho, Noel T Ross, Mieke van den Heuvel, Riad Benkouar, Hajo Findeisen, Imad A Alhaddad, Kais Al Balbissi , Gonzalo Barge-Caballero, Azmee M Ghazi, Liesbeth Bruckers , Pieter Martens , Wilfried Mullens. Rationale and Design of the Efficacy of a Standardized Diuretic Protocol in Acute Heart Failure Study. ESC Heart Fail. 2021 Dec;8(6):4685-4692. (IF 3.7)

7. Petar Risteski 1, Tanja Anguseva 2, Rodney Rosalia 2, Sonija Grazdani 3, Milka Klincheva 2, Venko Filipce 4, Marjan Sokarovski 3, Aron-Frederik Popov 5, Sasko Jovev 3, Zan Mitrev 2. Outcomes with Ventricular Assist Device Therapy for Advanced Heart Failure in North Macedonia: First Annual Report. Heart Surg Forum 2020 Jun 26;23(4): E441-E446.

8. Bosevski M, Mitevska I, Pavkovic M, Klincheva M, Lazarova ET, Velkova E, Stojanoski Z, Kostova N, Jordanova SP, Petkoska D, Mancheva M, Gulevska A, Baloski M, Hadjiev V, Krstevski G, Kralevska V, Bojovski I, Jovanovski M, Nedelkovska V, Gjorgievski A. Special Conditions in Venous Thrombembolism – Case Series. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2019 Oct 1;40(2):103-111. doi: 10.2478/prilozi-2019-0021.

9. Mitrev Z, Klincheva M, Anguseva T, Zdravkovski I, Rosalia RA. Cardiac autotransplantation and ex vivo surgical repair of giant left atrium: a case presentation. BMC Cardiovasc Disord. 2018 Dec 18;18(1):239. doi: 10.1186/s12872-018-0966-2. 

10. Мilka Klincheva, Elena-Ambarkova-Vilarova, Tanja Angjusheva, Ivan Milev, Enver Idoski, Zan Mitrev. Endothelial Nitric Oxide Synthase T-786C Mutation, Prothrombin Gene Mutation (G-20210-A) and Protein S Deficiency Could Lead to Myocardial Infarction in a Very Young Male Adult. . http://dx.doi.org/10.3889/oamjms.2016.014

11. Widimsky P, Wijns W, Fajadet J, de Belder M, Knot J, Aaberge L, Andrikopoulos G, Baz JA, Betriu A, Claeys M, Danchin N, Djambazov S, Erne P, Hartikainen J, Huber K, Kala P, Klinceva M, Kristensen SD, Ludman P, Ferre JM, Merkely B, Milicic D, Morais J, Noc M, Opolski G, Ostojic M, Radovanovic D, De Servi S, Stenestrand U, Studencan M, Tubaro M, Vasiljevic Z, Weidinger F, Witkowski A, Zeymer U; on behalf of the European Association for Percutaneous Cardiovascular Interventions. Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries. Eur Heart J. 2010 Apr;31(8):943-57.

12. Klinčeva M, Widimský P, Želízko M, Jánský P, Holm F, Toušek F, Aschermann M on behalf of the CZECH Registry Investigators. Electrocardiographic evolution of acute myocardial infarction in primary PCI era: data from the CZECH Registry of Acute Coronary Syndromes. Abstract Supplement European Heart Journal – Sept.2008 

13. Klinčeva M, Widimský P, Želízko M, Jánský P, Holm F, Toušek F, Aschermann M on behalf of the CZECH Registry Investigators. Modification of traditional ECG evolution of myocardial infarction by early intervention: analysis of the CZECH Registry of Acute Coronary Syndromes – ACC 2008, Chicago, USA. 

14. Milka Klinčeva, Petr Widimský, Ladislav Pešl, Josef Štásek, František Toušek, Milan Vambera, Danuše Bílková. Prevalence of Stress-Induced Myocardial Stunning (Tako-Tsubo Cardiomyopathy) Among Patients Undergoing Emergent Coronary Angiography For Suspected Acute Myocardial Infarction. Int J Cardiol. 2006 Nov 10; 

15. M. Klinčeva, P. Widimský, A. Dohnalová. Prospective use of EuroSCORE for the short-term risk evaluation of consecutive cardiac surgery candidates: are there any differences in prediction of perioperative risk versus risk of nonsurgical treatments? Vnitř Lék 2006;52(12):1156-61.

16. Interview: Cardiologists search for the answer to the riddle of the octopus bottle. ESC Congress News 03.09.2006, XVth World Congress of Cardiology, Barcelona, Spain. 

17. Milka Klinčeva, Petr Widimský, Ladislav Pešl, Josef Štásek, František Toušek, Milan Vambera, Danuše Bílková. Prevalence of Stress-Induced Myocardial Stunning (Tako-Tsubo Cardiomyopathy) Among Patients Undergoing Emergent Coronary Angiography For Suspected Acute Myocardial Infarction. Abstract Supplement European Heart Journal Vol.27.–Sept.2006 

18. Milka Klinčeva, Petr Widimský. European system for cardiac operative risk evaluation (EuroSCORE): a promising mortality predictive risk stratification tool? Cor Vasa 2005;47(3):108-110.

19. Меѓународни клинички студии:

1. Истражувач во студијата Signify: Ivabradine in Stable Coronary Artery Disease without Clinical Heart Failure (Signify study).
2. Истражувач во студијата MARINER: Rivaroxaban after hospital discharge for medical patients at high risk of VTE. Design, rationale, and clinical implications.

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